Muscle & strength

Lean mass, strength and growth hormone for body composition. Ranked by evidence grade, then user score. Each grade is for the use named on the card, which may not be this goal.

• Sleep
• Recovery & injury
• Fat loss
• Cognition & mood
• Libido & sexual health
• Longevity
• Skin & hair
• Immune
• Muscle & strength

Evidence grade Any grade A only B or better C or better D or better US FDA Any status Approved for this useApproved for another use onlyNot approved WADA (sport) Any status Not prohibitedProhibited or likely prohibitedNot named / unclear

7 of 7 peptides shown

1. B

   1.Ibutamoren mesylate

   Moderate human evidence · for raising GH/IGF-1 and lean mass

   FDA Not approved WADA Prohibited (S2.2.4)
   User score 3.5
   Outcomes: Positive 18 of 29 (62%), Mixed 6 of 29 (21%), Negative 3 of 29 (10%), No effect 2 of 29 (7%), Unclear 1 of 29 (3%)
   Men 45–60: 1 · everyone: 29 reports · approximate

   Why it’s listed: graded use mentions it; 12 of 29 user reports mention muscle; 14 of 29 user reports mention strength.

2. C

   2.Ipamorelin

   Preliminary human data · for raising growth hormone for sleep and body composition

   FDA Not approved WADA Prohibited (S2.2.4)
   User score 4.0
   Outcomes: Positive 34 of 48 (71%), Mixed 8 of 48 (17%), Negative 4 of 48 (8%), No effect 2 of 48 (4%)
   Men 45–60: 2 · everyone: 48 reports · approximate

   Why it’s listed: graded use mentions it; page tags mentions it; 14 of 48 user reports mention muscle; 13 of 48 user reports mention strength.

3. C

   3.CJC-1295

   Preliminary human data · for raising growth hormone for body composition, recovery and sleep

   FDA Not approved WADA Prohibited (S2.2.4)
   User score 2.5
   Outcomes: Positive 6 of 12 (50%), Mixed 1 of 12 (8%), Negative 2 of 12 (17%), Unclear 3 of 12 (25%)
   Men 45–60: 1 · everyone: 12 reports · approximate

   Why it’s listed: graded use mentions it; page tags mentions it; 3 of 12 user reports mention muscle.

4. C

   4.Sermorelin

   Preliminary human data · for adult growth-hormone 'optimisation', sleep and body composition

   FDA Approval withdrawn WADA Prohibited (S2.2.4)
   User score 2.0
   Outcomes: Positive 16 of 48 (33%), Mixed 10 of 48 (21%), Negative 16 of 48 (33%), No effect 3 of 48 (6%), Unclear 3 of 48 (6%)
   Men 45–60: 1 · everyone: 48 reports · approximate

   Why it’s listed: graded use mentions it.

5. D

   5.Follistatin-344

   Preclinical only · for injected protein for muscle growth

   FDA Not approved WADA Prohibited (S4.3)
   User scoretoo few reports (9)
   Men 45–60: 0 · everyone: 9 reports · approximate

   Why it’s listed: graded use mentions it; substance class mentions it; page tags mentions it; summary mentions it; 4 of 9 user reports mention muscle.

6. D

   6.IGF-1 LR3

   Preclinical only · for muscle growth and recovery

   FDA Not approved WADA Prohibited (S2.3)
   User scoretoo few reports (6)
   Men 45–60: 0 · everyone: 6 reports · approximate

   Why it’s listed: graded use mentions it; 5 of 6 user reports mention muscle; 2 of 6 user reports mention strength.

7. D

   7.PEG-MGF

   Preclinical only · for muscle recovery and growth

   FDA Not approved WADA Prohibited (S2.3)
   User scoretoo few reports (7)
   Men 45–60: 1 · everyone: 7 reports · approximate

   Why it’s listed: graded use mentions it; page tags mentions it; 2 of 7 user reports mention muscle.

User reports are anecdata, not evidence: self-selected, unverified, often combined with other compounds.